My husband works on DNA sequencers for a living.
Ask my husband what specifically he does, and he'll tell you in very straightforward terms about various DNA sequencing technologies and how they're used. No mystery there. No romance. Every question has an answer, every problem, a solution.
When he wants to make something, there's no pining about not having the skills, no aching about bringing his idea to fruition. He studies, he gets the right tools, he practices, and then he makes it.
See here, he wanted to make our bed. He turned a couple prototypes, and then he started making the bed--just like that.